IS 26 -Mediated Precise Excision of the IS 26 - aphA1a Translocatable Unit

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IS26-Mediated Precise Excision of the IS26-aphA1a Translocatable Unit

UNLABELLED We recently showed that, in the absence of RecA-dependent homologous recombination, the Tnp26 transposase catalyzes cointegrate formation via a conservative reaction between two preexisting IS26, and this is strongly preferred over replicative transposition to a new site. Here, the reverse reaction was investigated by assaying for precise excision of the central region together with ...

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ژورنال

عنوان ژورنال: mBio

سال: 2015

ISSN: 2161-2129,2150-7511

DOI: 10.1128/mbio.01866-15